← All Supplements
TMG (Trimethylglycine / Betaine)
A methyl donor that helps your body recycle homocysteine — an amino acid that, when too high, increases cardiovascular and cognitive risk.
Benefits
- +Donates methyl groups to lower homocysteine levels
- +Supports healthy liver function and fat metabolism
- +May support cardiovascular health by reducing homocysteine
- +Involved in DNA methylation and gene expression
- +May support healthy blood sugar levels
- +Important for SAMe production in the body
Dosage & Cost
Range500–1500 mg/day
TimingMorning or with meals — avoid in the evening
Daily cost0.10–0.35
Also known as anhydrous betaine. Works synergistically with B vitamins (especially B12 and folate) for homocysteine metabolism. Start with a lower dose.
Side Effects
- !Can cause nausea or digestive upset
- !May increase LDL cholesterol in some people
- !Can cause a sensation of warmth or flushing
- !May worsen certain autoimmune conditions — consult a doctor
- !Can cause insomnia if taken late in the day
Food Sources
- • Beetroot (richest source)
- • Spinach
- • Wheat germ
- • Quinoa
- • Sweet potatoes
References & Links
Community
Popularity rankings
#— in Coenzyme
#— overall
Stats accumulate as members log their stacks
—
take daily
—
cycle it
—
avg. stacks
In 1 public stack
This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.