Resveratrol
The compound found in red wine that sparked a huge wave of longevity research — it activates sirtuins and has real antioxidant power, though the supplement dose story is more nuanced than headlines suggest.
Benefits
- +Activates sirtuins, a family of genes linked to longevity
- +Powerful antioxidant
- +May support cardiovascular health and blood vessel function
- +Some evidence for anti-inflammatory effects
- +May support insulin sensitivity
- +Preliminary research on neuroprotective effects
Dosage & Cost
The bioavailability challenge is real — look for formulations with piperine or other absorption enhancers. Some experts think trans-resveratrol is the most effective form. The hype has outpaced the evidence slightly, but it's still a reasonable antioxidant supplement.
Side Effects
- !Digestive upset or diarrhea
- !Headache
- !May interact with blood-thinning medications
- !May affect hormonal balance — caution for those with estrogen-sensitive conditions
- !Bioavailability is actually quite low — much is metabolized before reaching the bloodstream
Food Sources
- • Red wine (small amounts — not a practical source)
- • Red grapes
- • Blueberries and raspberries
- • Dark chocolate
- • Peanuts
- • Note: food levels are far too low for therapeutic effect
References & Links
Community
Popularity rankings
Stats accumulate as members log their stacks
In 1 public stack
Featured Videos
Resveratrol – The Unfortunate (& Scandalous) Story
Dr Brad Stanfield
Side Effects of Resveratrol Supplements
NutritionFacts.org
Do resveratrol and NAD precursors promote longevity?
Peter Attia MD
This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.