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Grape Seed Extract (OPC)
A concentrated extract rich in oligomeric proanthocyanidins (OPCs) — potent antioxidants that are especially good for your blood vessels and skin.
Benefits
- +Supports vascular health and circulation
- +Strong antioxidant protection for blood vessels
- +May reduce swelling and bruising
- +Supports skin health and collagen integrity
- +Some evidence for reducing varicose vein symptoms
Dosage & Cost
Range100–300 mg/day (standardized to 95% OPCs)
TimingMorning, with or without food
Daily cost0.15–0.50
Look for extracts standardized to 95% proanthocyanidin content. Particularly popular in Europe for venous insufficiency.
Side Effects
- !Generally very safe
- !May thin the blood slightly — relevant if you're on blood thinners
- !Rare: headaches or digestive upset
- !May interact with certain medications — check with your pharmacist
Food Sources
- • Red grapes and grape skin
- • Red wine (though alcohol negates most health benefits)
- • Blueberries and cranberries (contain similar but different polyphenols)
- • Supplement is the most practical way to get therapeutic OPC doses
References & Links
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This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.