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Glycine

The simplest amino acid and one of the most underrated supplements — it supports sleep, joint health (it's a major building block of collagen), and has a surprising range of benefits for very little money.

Benefits

  • +Significantly improves sleep quality and helps you fall asleep faster
  • +Essential building block of collagen (supports joints, skin, gut)
  • +May support blood sugar regulation
  • +Has calming effects on the nervous system
  • +May support cognitive function and memory
  • +Plays a role in detoxification and bile acid production

Dosage & Cost

Range1–3 g/day
TimingBefore bed for sleep — the evidence for sleep improvement is at 3 g taken 1 hour before sleep
Daily cost$0.05–$0.15

Glycine is incredibly cheap — it's one of the best value supplements out there. The sleep research is genuinely solid (it lowers core body temperature, which promotes sleep). Also consider it as part of a collagen support stack.

Side Effects

  • !Drowsiness — it's calming, so take it at night
  • !Mild stomach upset in some people
  • !May lower blood pressure slightly
  • !Very few serious side effects — one of the safest supplements
  • !Possible headache

Food Sources

  • Collagen-rich foods (bone broth, connective tissues)
  • Eggs
  • Meat (especially with connective tissue)
  • Legumes
  • Note: most people don't get enough from diet alone, especially if not eating nose-to-tail

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This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.