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Fisetin

A flavonoid found in strawberries and other fruits that's gained serious attention in longevity research for its ability to clear out damaged, aging cells.

Benefits

  • +Acts as a senolytic — helps your body clear senescent ('zombie') cells
  • +Powerful anti-inflammatory and antioxidant
  • +May support neuroprotection and memory
  • +Animal studies suggest life-extending properties
  • +Increasingly studied in human clinical trials for aging

Dosage & Cost

Range100–500 mg/day
TimingCan be taken with or without food
Daily cost0.30–1.00

Many longevity researchers use intermittent dosing (e.g., 2–3 days on, rest of the week off) rather than daily. The research is promising but still young — use with reasonable expectations.

Side Effects

  • !Generally well tolerated in short-term studies
  • !May cause mild digestive upset
  • !Long-term safety data in humans is still emerging
  • !Could theoretically interact with chemotherapy drugs — discuss with oncologist

Food Sources

  • Strawberries (richest common source)
  • Apples
  • Onions
  • Persimmons
  • Present in small amounts — supplement is needed for researched doses

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This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.