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Ergothioneine

A rare mushroom-derived antioxidant that your body actively transports into cells, earning it the nickname "the longevity vitamin" among researchers.

Benefits

  • +Powerful cellular antioxidant that accumulates in tissues under oxidative stress
  • +May support brain health and protect against age-related cognitive decline
  • +May support cardiovascular and mitochondrial health
  • +Higher blood levels are associated with lower risk of chronic disease
  • +May help protect against inflammation

Dosage & Cost

Range5–30 mg/day
TimingWith or without food
Daily cost$0.40–$1.00

Dietary intake from mushrooms is typically 1–5 mg/day; supplements provide higher amounts. Body has a dedicated transporter (OCTN1) for it.

Side Effects

  • !Very well tolerated with no serious adverse effects reported
  • !Considered safe due to its natural presence in the diet
  • !Limited long-term high-dose safety data
  • !Mild digestive upset possible in sensitive individuals

Food Sources

  • Oyster and shiitake mushrooms (richest sources)
  • Button mushrooms
  • Tempeh and other fermented soy
  • Organ meats
  • Beans

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This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.