Calcium Alpha-Ketoglutarate
A metabolite that sits at the crossroads of energy production and cellular repair — it's gained attention in longevity circles for its role in the TCA cycle and potential anti-aging effects.
Benefits
- +Supports cellular energy production (feeds the TCA/Krebs cycle)
- +May support healthy aging and cellular repair
- +Some evidence for supporting bone health and reducing bone loss
- +May help with protein utilization and muscle recovery
- +Emerging research in anti-aging and metabolic health
Dosage & Cost
Research is still emerging. Some studies used it in combination protocols. The calcium form is gentler on the stomach than the free acid.
Side Effects
- !Can cause digestive upset, bloating, or loose stools
- !May affect blood sugar levels
- !Limited long-term human study data — relatively new in the supplement space
- !May interact with medications that affect calcium metabolism
Food Sources
- • Alpha-ketoglutarate is produced naturally by your body
- • Found in small amounts in fruits and vegetables
- • Supplementation is needed for therapeutic doses
References & Links
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This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.