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Apigenin
A gentle, calming flavonoid found in chamomile that's become a popular nighttime supplement for winding down without heavy sedation.
Benefits
- +Promotes relaxation and calm without drowsiness
- +May improve sleep onset and quality
- +Has anti-anxiety effects — works on GABA receptors similarly to mild benzodiazepines
- +Anti-inflammatory properties
- +May support healthy hormone levels
Dosage & Cost
Range50–200 mg/day
TimingEvening, 30–60 minutes before bed
Daily cost0.10–0.30
Popular in Andrew Huberman's sleep cocktail (with L-theanine and glycine). Works best as part of a calming bedtime routine.
Side Effects
- !Generally very well tolerated
- !Possible mild drowsiness — save it for evening
- !May interact with blood-thinning medications
- !Could affect hormone-sensitive conditions at high doses
Food Sources
- • Chamomile tea (the classic source)
- • Parsley
- • Celery
- • Artichokes
- • Present in many plants but at low concentrations
References & Links
Community
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This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.