Caffeine (Anhydrous)
The world's most popular performance enhancer — in its pure, concentrated form it's a clean way to boost alertness, focus, and physical output.
Benefits
- +Sharply improves alertness and mental focus
- +Boosts physical endurance and reaction time
- +May increase metabolic rate slightly
- +Well-proven ergogenic aid for sports and exercise
- +Can improve mood in moderate doses
Dosage & Cost
The sweet spot for most people is 100–200 mg. Anhydrous caffeine is ~99% pure caffeine — about the equivalent of 1–4 cups of coffee. Stop use at least 8–10 hours before bed.
Side Effects
- !Anxiety, jitters, and restlessness — especially at high doses
- !Disrupts sleep if taken too late in the day
- !Increases heart rate and blood pressure
- !Tolerance builds quickly with daily use
- !Withdrawal symptoms: headaches, fatigue, irritability
- !Potentially dangerous in very high doses (>400 mg)
Food Sources
- • Coffee (the most common source)
- • Black and green tea
- • Espresso
- • Energy drinks
- • Dark chocolate (smaller amounts)
- • Cola (smaller amounts)
References & Links
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Featured Videos

Using Caffeine to Optimize Mental & Physical Performance
Andrew Huberman

How to Use Caffeine & Coffee to Improve Focus | Dr. Andrew Huberman
Huberman Lab Clips
This page is for informational purposes only. The information here has not been evaluated by the Food and Drug Administration (FDA). No supplement discussed on this page is intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor or a qualified healthcare professional before taking any dietary supplement.